A Review on Organogels: Lipid Based Carrier Systems

Organogel is a viscoelastic carrier system, can be regarded as a semi-solid preparation which has an immobilized external organic (apolar) phase. Organogels have evolved as one of the potential carrier system for topical delivery. When compared to other lipid based carrier systems, these prove to be better in terms of efficacy, feasibility and shelf life. Organogelator such as n-alkanes, fatty acids are used for preparation of organogels. Organogel is a non crystalline, non-glassy, thermoplastic solid material composed of a liquid organic phase entrapped in a three-dimensionally cross-linked network. Organogel consists of both hydrophobic and hydrophilic components; both hydrophobic and hydrophilic drugs can be incorporated. Characterization of organogels contains Rheological Behaviour, Physiochemical properties, Optical Clarity and In vitro drug release.